You can delete publications programmatically by using Replication Management Objects (RMO). The RMO classes that you use to remove a publication depend on the type of publication you remove.
To remove a snapshot or transactional publication
- Create a connection to the Publisher by using the ServerConnection class. 
- Create an instance of the TransPublication class. 
- Set the Name and DatabaseName properties for the publication, and set the ConnectionContext property to the connection created in step 1. 
- Check the IsExistingObject property to verify that the publication exists. If the value of this property is false, either the publication properties in step 3 were defined incorrectly or the publication does not exist. 
- Call the Remove method. 
- (Optional) If no other transactional publications exist for this database, the database can be disabled for transactional publishing as follows: - Create an instance of the ReplicationDatabase class. Set the ConnectionContext property to the instance of ServerConnection from step 1.
- Call the LoadProperties method. If this method returns false, confirm that the database exists.
- Set the EnabledTransPublishing property to false.
- Call the CommitPropertyChanges method.
 
- Close the connections. 
To remove a merge publication
- Create a connection to the Publisher by using the ServerConnection class. 
- Create an instance of the MergePublication class. 
- Set the Name and DatabaseName properties for the publication, and set the ConnectionContext property to the connection created in step 1. 
- Check the IsExistingObject property to verify that the publication exists. If the value of this property is false, either the publication properties in step 3 were defined incorrectly or the publication does not exist. 
- Call the Remove method. 
- (Optional) If no other merge publications exist for this database, the database can be disabled for merge publishing as follows: - Create an instance of the ReplicationDatabase class. Set the ConnectionContext property to the instance of ServerConnection from Step 1.
- Call the LoadProperties method. If this method returns false, verify that the database exists.
- Set the EnabledMergePublishing property to false.
- Call the CommitPropertyChanges method.
 
- Close the connections. 
示例
The following example deletes a transactional publication. If no other transactional publications exist for this database, transactional publishing is also disabled.
// Define the Publisher, publication database, 
// and publication names.
string publisherName = publisherInstance;
string publicationName = "AdvWorksProductTran";
string publicationDbName = "AdventureWorks";
TransPublication publication;
ReplicationDatabase publicationDb;
// Create a connection to the Publisher 
// using Windows Authentication.
ServerConnection conn = new ServerConnection(publisherName);
try
{
    conn.Connect();
    // Set the required properties for the transactional publication.
    publication = new TransPublication();
    publication.ConnectionContext = conn;
    publication.Name = publicationName;
    publication.DatabaseName = publicationDbName;
    // Delete the publication, if it exists and has no subscriptions.
    if (publication.LoadProperties() && !publication.HasSubscription)
    {
        publication.Remove();
    }
    else
    {
        // Do something here if the publication does not exist
        // or has subscriptions.
        throw new ApplicationException(String.Format(
            "The publication {0} could not be deleted. " +
            "Ensure that the publication exists and that all " +
            "subscriptions have been deleted.",
            publicationName, publisherName));
    }
    // If no other transactional publications exists,
    // disable publishing on the database.
    publicationDb = new ReplicationDatabase(publicationDbName, conn);
    if (publicationDb.LoadProperties())
    {
        if (publicationDb.TransPublications.Count == 0)
        {
            publicationDb.EnabledTransPublishing = false;
        }
    }
    else
    {
        // Do something here if the database does not exist.
        throw new ApplicationException(String.Format(
            "The database {0} does not exist on {1}.",
            publicationDbName, publisherName));
    }
}
catch (Exception ex)
{
    // Implement application error handling here.
    throw new ApplicationException(String.Format(
        "The publication {0} could not be deleted.",
        publicationName), ex);
}
finally
{
    conn.Disconnect();
}
' Define the Publisher, publication database, 
' and publication names.
Dim publisherName As String = publisherInstance
Dim publicationName As String = "AdvWorksProductTran"
Dim publicationDbName As String = "AdventureWorks"
Dim publication As TransPublication
Dim publicationDb As ReplicationDatabase
' Create a connection to the Publisher 
' using Windows Authentication.
Dim conn As ServerConnection = New ServerConnection(publisherName)
Try
    conn.Connect()
    ' Set the required properties for the transactional publication.
    publication = New TransPublication()
    publication.ConnectionContext = conn
    publication.Name = publicationName
    publication.DatabaseName = publicationDbName
    ' Delete the publication, if it exists and has no subscriptions.
    If publication.LoadProperties() And Not publication.HasSubscription Then
        publication.Remove()
    Else
        ' Do something here if the publication does not exist
        ' or has subscriptions.
        Throw New ApplicationException(String.Format( _
         "The publication {0} could not be deleted. " + _
         "Ensure that the publication exists and that all " + _
         "subscriptions have been deleted.", _
         publicationName, publisherName))
    End If
    ' If no other transactional publications exists,
    ' disable publishing on the database.
    publicationDb = New ReplicationDatabase(publicationDbName, conn)
    If publicationDb.LoadProperties() Then
        If publicationDb.TransPublications.Count = 0 Then
            publicationDb.EnabledTransPublishing = False
        End If
    Else
        ' Do something here if the database does not exist.
        Throw New ApplicationException(String.Format( _
         "The database {0} does not exist on {1}.", _
         publicationDbName, publisherName))
    End If
Catch ex As Exception
    ' Implement application error handling here.
    Throw New ApplicationException(String.Format( _
     "The publication {0} could not be deleted.", _
     publicationName), ex)
Finally
    conn.Disconnect()
End Try
The following example deletes a merge publication. If no other merge publications exist for this database, merge publishing is also disabled.
// Define the Publisher, publication database, 
// and publication names.
string publisherName = publisherInstance;
string publicationName = "AdvWorksSalesOrdersMerge";
string publicationDbName = "AdventureWorks";
MergePublication publication;
ReplicationDatabase publicationDb;
// Create a connection to the Publisher.
ServerConnection conn = new ServerConnection(publisherName);
try
{
    // Connect to the Publisher.
    conn.Connect();
    // Set the required properties for the merge publication.
    publication = new MergePublication();
    publication.ConnectionContext = conn;
    publication.Name = publicationName;
    publication.DatabaseName = publicationDbName;
    // Delete the publication, if it exists and has no subscriptions.
    if (publication.LoadProperties() && !publication.HasSubscription)
    {
        publication.Remove();
    }
    else
    {
        // Do something here if the publication does not exist
        // or has subscriptions.
        throw new ApplicationException(String.Format(
            "The publication {0} could not be deleted. " +
            "Ensure that the publication exists and that all " +
            "subscriptions have been deleted.",
            publicationName, publisherName));
    }
    // If no other merge publications exists,
    // disable publishing on the database.
    publicationDb = new ReplicationDatabase(publicationDbName, conn);
    if (publicationDb.LoadProperties())
    {
        if (publicationDb.MergePublications.Count == 0 && publicationDb.EnabledMergePublishing)
        {
            publicationDb.EnabledMergePublishing = false;
        }
    }
    else
    {
        // Do something here if the database does not exist.
        throw new ApplicationException(String.Format(
            "The database {0} does not exist on {1}.",
            publicationDbName, publisherName));
    }
}
catch (Exception ex)
{
    // Implement application error handling here.
    throw new ApplicationException(String.Format(
        "The publication {0} could not be deleted.",
        publicationName), ex);
}
finally
{
    conn.Disconnect();
}
' Define the Publisher, publication database, 
' and publication names.
Dim publisherName As String = publisherInstance
Dim publicationName As String = "AdvWorksSalesOrdersMerge"
Dim publicationDbName As String = "AdventureWorks"
Dim publication As MergePublication
Dim publicationDb As ReplicationDatabase
' Create a connection to the Publisher.
Dim conn As ServerConnection = New ServerConnection(publisherName)
Try
    ' Connect to the Publisher.
    conn.Connect()
    ' Set the required properties for the merge publication.
    publication = New MergePublication()
    publication.ConnectionContext = conn
    publication.Name = publicationName
    publication.DatabaseName = publicationDbName
    ' Delete the publication, if it exists and has no subscriptions.
    If (publication.LoadProperties() And Not publication.HasSubscription) Then
        publication.Remove()
    Else
        ' Do something here if the publication does not exist
        ' or has subscriptions.
        Throw New ApplicationException(String.Format( _
         "The publication {0} could not be deleted. " + _
         "Ensure that the publication exists and that all " + _
         "subscriptions have been deleted.", _
         publicationName, publisherName))
    End If
    ' If no other merge publications exists,
    ' disable publishing on the database.
    publicationDb = New ReplicationDatabase(publicationDbName, conn)
    If publicationDb.LoadProperties() Then
        If publicationDb.MergePublications.Count = 0 _
        And publicationDb.EnabledMergePublishing Then
            publicationDb.EnabledMergePublishing = False
        End If
    Else
        ' Do something here if the database does not exist.
        Throw New ApplicationException(String.Format( _
         "The database {0} does not exist on {1}.", _
         publicationDbName, publisherName))
    End If
Catch ex As Exception
    ' Implement application error handling here.
    Throw New ApplicationException(String.Format( _
     "The publication {0} could not be deleted.", _
     publicationName), ex)
Finally
    conn.Disconnect()
End Try
请参阅
任务
How to: Create a Publication (RMO Programming)
How to: Delete a Publication (Replication Transact-SQL Programming)