Hi MS,
Welcome to Microsoft Q&A Platform. Thank you for reaching out & hope you are doing well.
The error 'Internal server error executing the request' usually means Synapse had trouble starting the compute that runs your data flow. Since this only happens in one of your workspaces, it’s likely something in that workspace’s setup or environment.
Please check if the debug cluster is able to start from the Data Flow Debug or Integration Runtime section in Synapse Studio. If the cluster can’t start, it could be due to limited capacity in the region, missing permissions, or a network rule blocking Synapse from creating the compute.
If the workspace uses a Managed Virtual Network or private endpoints, please make sure the needed Azure services (like Storage and Synapse control plane) are allowed through your firewall or NSG. Sometimes blocked outbound traffic causes this exact error.
Try creating and running a very simple data flow (for example, one that just reads and writes data). If that fails too, it confirms the issue is with the workspace setup or compute, not your pipeline.
Also, check the Azure Service Health page for UK South to make sure there’s no ongoing Synapse issue in that region.
Kindly let me know if you have any further questions. I’ll be glad to assist you.
Thanks,
Manoj