Dear Larry,
We understand you're experiencing issues with Multipath I/O (MPIO) on your Windows Server 2025 Datacenter installation after uninstalling the feature via PowerShell. Based on your description, the system now fails to reinstall MPIO, even when pointing to a local ISO source, and the registry appears clean.
This behavior may be related to a known issue where remnants of the MPIO device instance prevent reinstallation. Microsoft has documented this under Error 0x800f0922 during MPIO feature installation. The error typically occurs when the system detects a conflicting or orphaned device entry.
We recommend the following steps:
Use Device Manager to enable “Show hidden devices” and remove any residual MPIO-related entries under “Storage controllers.”
Run sfc /scannow and DISM /Online /Cleanup-Image /RestoreHealth to repair system components.
Attempt reinstalling MPIO using: Install-WindowsFeature -Name Multipath-IO -Source D:\sources\sxs (Replace D: with your actual ISO mount path.)
If this message is useful for you, please give it a vote.
Best regards,
Quinnie Quoc.